The HADD-Coil can be used to help patients suffering from:
- Nicotine Addiction
- Drug Addiction (Cocaine, Opiate, Cannabis, Benzodiazepine, Amphetamine)
- Eating Disorders, including Obesity, Anorexia Nervosa, and Bulimia
Transcranial Magnetic Stimulation For The Treatment Of Addictive Disorders
Drugs of abuse activate the mesolimbic dopamine circuit, which originates in the ventral segmental area and projects to the reward circuit of the brain, including the nucleus accumbens, amygdala, hippocampus and prefrontal cortex. Decreased activity in the brain reward circuit during withdrawal is associated with cravings, relapse and continued use. Transcranial magnetic stimulation studies show decreased cortical excitability in substance dependent patients when compared to normal controls. Specifically, the disease of addiction is one in which there is insufficient dopamine release by the reward circuits until the addictive substance is used. When the addictive substance is used, it may give them a greater feeling of reward than anything in their natural life.
Repetitve transcranial magnetic stimulation (rtms), and specifically deep repetitive magnetic stimulation (dtms) induces long lasting neuroplastic changes in both cortical and subcortical neurons and can reach structures 4cm beneath the surface of the skull. The specific addiction coil that is used for these disorders targets bilateral prefrontal cortexes and the bilateral insular cortex. Prior to each treatment, patients are given cues that trigger their addiction cravings. The subsequent stimulation causes dopamine release without the need for them to use the substance. This makes them desensitized to the addictive triggers or cues and is the reason they remain abstinent.
What addictions can the dTMS coil be used for?
dTMS can be used for the treatment of any addiction to a substance. This includes nicotine, cocaine, alcohol, opiates, amphetamines, benzodiazapines and cannabis. This coil is currently CE approved in Europe and in Israel for nicotine dependence. We are also willing to try to treat gambling and binge eating-food addiction but we do not have enough information to know if it will work for those indications.
How many treatments will be necessary?
With any disorder and treatments, the timing of response is varied. We recommend three weeks of treatments at five days a week. At this juncture we should see a reduction in drug use evident in urine drug tests. After this point treatment can be continued, discontinued or tapered to twice or once a week depending on the individual patient’s response.
Do you have any ongoing clinical trials that are free?
We have a clinical trial for smoking cessation, bipolar depression and obsessive compulsive disorder that are recruiting. You can contact us to see if you are eligible.
Figure 1. A sketch of the HADD-Coil, which can activate the right and left insular cortex, as well as the prefrontal cortex, with bilateral symmetry.